INTRODUCTION TO CLINICAL PATHOLOGY
Academic Year 2023/2024 - Teacher: STEFANIA STELLAExpected Learning Outcomes
The course develops skills in the Clinical Pathology aiming to teach the
student to apply, evaluate and interpret the laboratory tests used to
study of the main diseases of the blood, alterations of the
coagulative-fibrinolytic system, changes in liver and kidney function,
some endocrinopathies, oncological and cardiovascular diseases.
Course Structure
The lessons are held in the classroom with the help of PDF presentations
made available to students. The presentations do not replace the
reference texts, but serve as educational support for the program
carried out. Should teaching be carried out in mixed mode or remotely,
it may be necessary to introduce changes with respect to previous
statements, in line with the program planned and outlined in the
syllabus.
Required Prerequisites
Knowledge of biochemistry, cell biology, anatomy and physiology.
Attendance of Lessons
Attendance of lessons is mandatory.
Detailed Course Content
The course is organized into theoretical lessons combined with exercises aimed to interpreter the results of different types of laboratory and molecular test.
Program:
- RT - PCR- Real Time PCR
- Digital PCR
- Liquid biopsy
- Detections of gene mutations by Sanger sequencing and NGS sequencing in the main blood diseases
- Tumoral biomarkers
- Heredofamilial syndromes and Lynch syndromes
Textbook Information
1. Federici G. Medicina di Laboratorio. Mc Graw-Hill Companies
2.Ciaccio M., Lippi G Biochimica Clinica e Medicina di Laboratorio, EdiSES
3. Antonozzi I. Medicina di Laboratorio, Piccin
4. Flyers in PDF
Course Planning
| Subjects | Text References | |
|---|---|---|
| 1 | RT - PCR | |
| 2 | Real Time PCR | |
| 3 | Digital PCR | |
| 4 | Liquid Biopsy | |
| 5 | Detections of gene mutations by Sanger sequencing and NGS sequencing in the main blood diseases | |
| 6 | Tumoral Biomarkers | Testo 1: capitolo 15; Testo 2: capitolo 28, 29 |
| 7 | Heredofamilial syndromes and Lynch syndromes |
Learning Assessment
Learning Assessment Procedures
Oral examination.
Verification of learning can also be carried out electronically, should the conditions require it.
Examples of frequently asked questions and / or exercises
Heredofamilial syndromes, BRCA1 and BRCA2 genes
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