INTRODUCTION TO CLINICAL PATHOLOGY

Academic Year 2026/2027 - Teacher: LIVIA MANZELLA

Expected Learning Outcomes

1. Knowledge and understanding

The aim of the course is to acquire skills in the field of clinical pathology. Students will gain knowledge regarding the laboratory tests used to investigate major blood disorders, abnormalities of the coagulation-fibrinolysis system, impaired hepatic and renal function, certain endocrinopathies, and autoimmune diseases.

2. Applying knowledge and understanding

The student will be able to apply the knowledge acquired to evaluate and interpret key laboratory tests. They will also be able to recognize and evaluate key analytes in specific pathophysiological conditions.

3. Making judgements

The student will develop the ability to critically evaluate data derived from biological and biochemical analyses, interpreting results regarding analytes in biological samples and formulating judgments in relation to physiological and pathophysiological conditions.

4. Communication skills

The student will be able to communicate the knowledge acquired in the field of clinical pathology clearly and appropriately, using suitable scientific terminology, in both academic and professional contexts.

5. Learning skills

The student will develop independent learning skills that will enable them to continuously deepen and update their knowledge in the fields of clinical pathology and the life sciences, including in relation to the evolution of analytical techniques.

Equal Opportunities

To ensure equal opportunities and in compliance with current regulations, interested students may request an individual meeting to determine any compensatory and/or dispensatory measures, in relation to educational objectives and specific needs.

Course Structure

The lessons are held in the classroom with the help of PDF presentations made available to students on the Studium portal. The presentations do not replace the reference texts, but serve as educational support for the program carried out. Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.


 

Required Prerequisites

Knowledge of biochemistry, cell biology, anatomy, physiology and human pathophysiology.

Detailed Course Content

Laboratory analysis: definition, typology

Collection and conservation of biological samples

Preanalytical, analytical and biological variability

Complete blood count test

Plasma proteins and electrophoresis

The thyrod

Urine analysis and functional kidney test

The functional liver and  viral hepatitis tests

Diabetes: diagnosis and follow up test

Autoimmune disease test

Textbook Information

Course Planning

 SubjectsText References
1Introductory lesson to the study of Clinical Pathologytesti 1 e 2: capitolo 1
2Complete blood counttesto 1: capitolo 2; testo 2 capitolo 18
3Plasma Proteins and Electrophoresispresentazione in PDF della lezione
4The Thyroidpresentazione in PDF della lezione
5Diabetes: diagnosis and monitoringtesto 1: capitolo 8; testo 2: capitolo 5
6Liver function indices and viral hepatitistesto 1: capitolo 7; testo 2 capitolo 3
7Autoimmune Diseasespresentazione in PDF della lezione
8Indices of renal function and urinalysistesto 1: capitolo 6; testo 2: capitolo 4

Learning Assessment

Learning Assessment Procedures

Oral examination. The test consists of an interview in which 2-3 questions will be asked that deal with at least 2-3 different topics of the program. The test allows to verify: i) the level of knowledge of the program topics; ii) the ability to apply this knowledge in dealing with specific clinical situations; iii) clarity of presentation; iv) the property of medical-scientific language.

For the attribution of the final grade, the following parameters will be taken into account:

 Grade 29-30 with honors: the student has a thorough knowledge of the required topics, is able to promptly and correctly integrate and critically analyze the situations presented, autonomously solving even highly complex problems; has excellent communication skills and masters medical-scientific language.

Grade 26-28: the student has a good knowledge of the required topics, is able to integrate and analyze the situations presented in a critical and linear way, is able to solve complex problems independently and presents the arguments clearly using medical language. appropriate scientific;

Grade 22-25: the student has a fair knowledge of the required topics, even if limited to the main topics; she succeeds in integrating and analyzing in a critical but not always linear way the situations presented and she exposes the arguments quite clearly with a discrete property of language;

Grade 18-21: the student has the minimum knowledge of the required topics, has a modest ability to integrate and critically analyze the situations presented and presents the topics in a sufficiently clear way although the language properties are not very developed;

Failed exam: the student does not have the minimum required knowledge of the main teaching contents. The ability to use language

specific is very little or zero and is unable to independently apply the knowledge acquired.

 The final mark is given by the weighted average of the marks obtained in the 2 modules.

VERSIONE IN ITALIANO