Carmen Sica

PhD Student
PhD in Earth and Environmental Sciences - XXXVIII cycle
Tutor: Margherita Ferrante

Professional Experience

31/10/2022 – Present
PhD Candidate (38th cycle)
University of Catania – Department of Biological, Geological and Environmental Sciences (Hygiene Sector)
Project: In silico study for the evaluation of oncoprotective activity by analysis of highly purified algal phycocyanin through miRNAs regulation

6 months of research activity abroad at Universidad de Vigo, Ourense Campus (Spain) – Department of Chemical Engineering

18/01/2022 – 16/07/2022
Research Fellow
Laboratory of Cytology and Histology, Department of Biological, Geological and Environmental Sciences – University of Catania

01/09/2021 – 17/01/2022
Qualified Tutor of Developmental Biology
Bachelor’s Degree Course in Biological Sciences – University of Catania

08/01/2021 – 05/06/2021
Intern
Poliambulatorio Medisan (Catania) – RNA extraction, PCR, biochemical tests

01/09/2020 – 01/11/2020
Intern with job placement
Acoset S.P.A. – Quality control of drinking water


Education and Training

05/01/2021 – 10/01/2022
Advanced Course in Biotechnology and Assisted Reproduction Techniques
University of Naples Federico II

2018 – 2021

Master’s Degree in Reproductive Biology of Aquatic Environments – Grade: 100/110
University of Naples Federico II & University Parthenope

Experimental Thesis: Toxicity evaluation of TiO₂ nanoparticles on Zebrafish larvae using DanioScope (at University of Catania)

Skills acquired: ichthyopathology, developmental biology, oceanography, reproduction, physiology, biochemistry, hygiene

2013 – 2018
Bachelor’s Degree in Marine Biology and Ecology – Grade: 94/110
University of Messina

Skills: molecular biology, histology, physiology, chemistry, zoology, algae systematics, cartography

  • Oct 1, 2013 – Jul 16, 2018
    Bachelor’s Degree in Marine Biology and Ecology, grade: 94/110
    University of Messina
    Skills acquired: molecular biology, general and organic chemistry, mathematics, physics, zoology, botany, cytology and histology, coastal dynamics, algal systematics, cartography.
  • Jan 2016 – Sep 5, 2016
    Erasmus+ (Traineeship and Studium)
    University of Murcia, Spain
    Thesis internship in Aquaculture. Exams in Spanish: Aquaculture, Theoretical and Practical Geology.
  • October 14–15, 2016
    Educational Internship “Sommergiamoci”
    University of Messina and University Federico II of Naples
    Activities in the Marine Protected Areas of Gaiola (Naples).
  • 2007 – 2013
    High School Diploma in Socio-Psycho-Pedagogical Studies, grade: 78/100
    Regina Elena High School, Acireale
    Main subjects: pedagogy, philosophy, psychology, sociology, Italian, Latin.
  • Professional Registration
  • Jan 5, 2021 – Jan 10, 2022
    Registered in the Professional Biologists’ Board – Section B, reg. no. AB_088317
  • Apr 27, 2022
    Transferred to Section A of the Professional Biologists’ Board, reg. no. AA_093153
  • PERSONAL SKILLS

Mother Tongue

  • Italian
  • Other Languages

Language

Listening

Reading

Spoken Interaction

Spoken Production

Writing

English

C2

C2

C2

C2

C2

Spanish

B2

B2

B2

B2

B2

  • English: Certified C2 level by e-labor@ndo (certified training agency)
  • Spanish: Self-declared level
  • CEFR Scale: A1/A2 = Basic User, B1/B2 = Independent User, C1/C2 = Proficient User

Communication Skills

  • Strong ability to work in a team and interact with diverse individuals, developed through university study groups and internships in both private and public analysis laboratories.
  • Excellent interpersonal skills aimed at constructive dialogue, problem-solving, and collaborative comparison of laboratory test results.

Organizational and Managerial Skills

  • Proven ability to work independently and take responsibility both in personal and professional environments.
  • Experience in both individual and team settings, acquired through university projects and various professional roles.

Professional Skills

  • Evaluation of various sperm parameters (concentration, motility, vitality, acrosomal damage, DNA fragmentation, oxidative stress, apoptosis, mitochondrial activity).
  • Toxicity assays on gametes of different animal models (Mytilus galloprovincialis, Paracentrotus lividus, Danio rerio, human).
  • Toxicity tests on embryos of various species (Mytilus galloprovincialis, Paracentrotus lividus, Danio rerio, Artemia salina).
  • Preparation of histological slides: fixation, dehydration, paraffin embedding, microtome sectioning, histological and histochemical staining.
  • Sample embedding techniques for Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM).
  • Extraction of bioactive compounds from microalgae and cyanobacteria (phenolics, carotenoids, fatty acids, antioxidants) using both chemical and green extraction methods.

Digital Competence (Self-assessment)

Competence Area

Level

Information Processing

Intermediate

Communication

Intermediate

Content Creation

Intermediate

Safety

Intermediate

Problem Solving

Intermediate

  • Additional Digital Skills:
    • Good command of office software (word processor, spreadsheets, presentation tools)
    • Good command of digital image editing software, acquired as an amateur photographer

Digital Courses and Certifications

  • Course: Didactic Use of Tablets – 200 hours
  • Course: PL200 – Didactic Use of Interactive Whiteboards (LIM) – 200 hours
  • Course: Introduction to Coding – Programming with Scratch

Driving License

  • Categories A and B
  •  
  • Laboratory instrument use:
    • Spectrometry (ICP-OES)
    • Mass spectrometry (ICP-MS)
    • Spectrophotometry
    • High-Performance Liquid Chromatography (HPLC)
    • Book Chapters
    • Co-author of the university textbook “Environmental Hygiene”, First Edition, 2024.
      ISBN: 9788836232031
    • Awards

    • 1st Prize – Euro-Mediterranean Journal Paper Award, 2nd International One Health Conference (2023)
      The DECARB project as One Health approach in the industrial symbiosis
      Authors: Sica C., Oliveri Conti G., Copat C., Bonfante G., Nicotra P., Scollo M., Falqui L., Ferrante M.

    • Conferences

    • ICEB 2021, Cairo (Egypt)
      Effect of electromagnetic fields at 27 GHz on sperm quality of Mytilus galloprovincialis.
      Sica C., et al.
    • ICEB 2021, Cairo (Egypt)
      Non-invasive technique for heartbeat measurement in zebrafish embryos exposed to EMF at 27 GHz.
      Ignoto S., Sica C., et al.
    • XXVI SIPI National Congress, Messina, June 2022
      Biological effects of non-ionizing EMFs on reproduction in Mytilus galloprovincialis.
      Sica C., et al.
    • XXVI SIPI National Congress, Messina, June 2022
      Embryotoxicity assessment of TiO nanoparticles in zebrafish larvae.
      Ferruggia G., Sica C., et al.
    • 1st National Conference on Emerging Contaminants, ONB Catania
      Toxicity evaluation of brookite TiO nanoparticles combined with CeO on marine invertebrate sperm.
      Indelicato S., Sica C., et al.
    • 1st National Conference on Emerging Contaminants, ONB Catania
      Toxicity of polystyrene nanospheres on human spermatozoa.
      Contino M., Sica C., et al.
    • 2nd International One Health Conference, Barcelona, October 2023
      The DECARB Project as One Health Approach in Industrial Symbiosis.
      Sica C., et al.
    • 2nd International One Health Conference, Barcelona, October 2023
      Conversion of CO emissions into algal biomass for the production of anti-cancer bioactives.
      Copat C., Sica C., et al.
    • International Conference: Climate Change and Environmental Pollutants, Sousse, Tunisia, November 2023
      Microalgae solutions to fight climate change: cultivation of Haematococcus pluvialis.
      Copat C., Sica C., et al.
    • VII Annual Meeting, UVigo Campus, Vigo, Spain, July 2024
      From Photobioreactors to Preventive Medicine: The Role of Microalgae in the Energy Transition.
      Sica C., et al.
    • 3rd Iberian Meeting on Supercritical Fluids, Ourense, Spain, July 2024
      Supercritical-CO extraction of lipids, phenolics, and pigments from Rugulopteryx okamurae.
      Inoubli S., Sica C., et al.
    • 5th Ibero-American Congress on Biorefineries (5-CIAB), Jaén, Spain, October 2024
      Arthrospira platensis biorefinery for production of green cosmetics.
      Sica C., et al.
    • 3rd International One Health Conference, Athens, Greece, October 2024
      Innovative method in microalgae processing for environmental and health applications.
      Sica C., et al.
    • Feb 14, 2025
      62nd Course – International School of Epidemiology and Preventive Medicine “Giuseppe D’Alessandro”
      Topic: Water and food in light of climate change: resilience and public health interventions
    • Mar 27–28, 2025
      1st National Conference – Italian Ministry of Health
      National Prevention System for Health Protection from Environmental and Climate Risks (SNPS)
    • Nov 25–29, 2024
      “eXXperimenta en femenino” – Spain
    • Sep 20, 2024
      VI Xornadas de Biomas de Desenvolvemento Sostible (BioDSpst24) – Spain
    • Conferences and Scientific Presentations

      1. Sica C., Scalisi E.M., Ignoto S., Palmeri L., Contino M., Ferruggia G., Salvaggio A., Pavone S.C., Sorbello G., Di Donato L., Pecoraro R., Brundo M.V.
      Effect of electromagnetic fields at 27 GHz on sperm quality of Mytilus galloprovincialis.
      ICEB 2021 – 15th International Conference on Environment and Bioengineering, December 13–14, 2021, Cairo (Egypt).

      2. Ignoto S., Scalisi E.M., Sica C., Contino M., Ferruggia G., Salvaggio A., Pavone S.C., Sorbello G., Di Donato L., Pecoraro R., Brundo M.V.
      Non-invasive technique for measuring heartbeat in zebrafish embryos exposed to electromagnetic fields at 27 GHz.
      ICEB 2021 – 15th International Conference on Environment and Bioengineering, December 13–14, 2021, Cairo (Egypt).

      3. Sica C., Pecoraro R., Pavone C.S., Sorbello G., Di Donato L., Ignoto S., Scalisi E.M., Ferruggia G., Contino M., Salvaggio A., Brundo M.V.
      Biological effects of non-ionizing electromagnetic fields on reproduction of Mytilus galloprovincialis.
      XXVI National SIPI Congress, June 23–25, 2022, Messina (Italy).

      4. Ferruggia G., Pecoraro R., Contino M., Ignoto S., Sica C., Truglio E., Ilaria C., Brundo M.V., Salvaggio A.
      Traditional and innovative techniques for evaluating the embryotoxicity of TiO₂ nanoparticles on zebrafish larvae.
      XXVI National SIPI Congress, June 23–25, 2022, Messina (Italy).

      5. Indelicato S., Sica C., Contino M., Ferruggia G., Pecoraro R., Scalisi E.M., Brundo M.V., Pennisi S., Coppa F., Giuffrida G.
      Toxicity evaluation of Brookite-phase TiO₂ nanoparticles combined with CeO₂ on sperm cells of marine invertebrates.
      1st National Conference “Emerging Contaminants: Environment, Nutrition, Health”, ONB, Catania (Italy).

      6. Contino M., Ferruggia G., Sica C., Indelicato S., Pecoraro R., Scalisi E.M., Brundo M.V.
      Toxicity of polystyrene nanospheres on human sperm cells.
      1st National Conference “Emerging Contaminants: Environment, Nutrition, Health”, ONB, Catania (Italy).

      7. Sica C., Oliveri Conti G., Copat C., Bonfante G., Ferrante M.
      The DECARB Project as a One Health approach in industrial symbiosis.
      2nd International One Health Conference, October 19–20, 2023, Barcelona (Spain).

      8. Copat C., Grasso A., Falqui L., Scollo M., Favara C., Sica C., Cristaldi A., Fiore M., Oliveri Conti G., Ferrante M.
      Conversion of greenhouse gas emissions (CO₂) into algal biomass for the production of bioactive antitumor compounds: Implementing green industrial symbiosis to support preventive medicine (GrEEnoncoprev – REACT-EU).
      2nd International One Health Conference, October 19–20, 2023, Barcelona (Spain).

      9. Copat C., Scollo M., Bonfante G., Favara C., Sica C., Grasso A., Oliveri Conti G., Ferrante M.
      Microalgae solution to fight climate change and support green economy: new challenges with Haematococcus pluvialis cultivation.
      International Conference: Climate Change and Environmental Pollutants – Main Drivers of Biodiversity Decline, November 2023, Sousse (Tunisia).

      10. Sica C., Inoubli S., Favara C., Copat C., Torres M.D., Bonfante G., Falqui L., Scollo M., Oliveri Conti G., Dominguez H., Ferrante M.
      From Photobioreactors to Preventive Medicine: The Role of Microalgae in the Energy Transition.
      VII Annual Meeting, July 18–19, 2024, University of Vigo, Campus of Marcosende (Spain).

      11. Inoubli S., Sica C., Florez-Fernandez N., Diaz-Reinos B., Torres M.D., Dominguez H.
      Supercritical-CO₂ extraction of lipidic, phenolic, and pigment fractions from Rugulopteryx okamurae.
      3rd Iberian Meeting on Supercritical Fluids, July 22–24, 2024, Ourense (Spain).

      12. Sica C., Favara C., Copat C., Torres M.D., Florez-Fernandez N., Bonfante G., Falqui L., Scollo M., Oliveri Conti G., Dominguez H., Ferrante M.
      Arthrospira platensis biorefinery for the production of green cosmetics-based products.
      5th Iberoamerican Congress on Biorefineries (5-CIAB), October 2–4, 2024, Jaén (Spain).

      13. Sica C., Favara C., Inoubli S., Copat C., Torres M.D., Bonfante G., Falqui L., Scollo M., Oliveri Conti G., Dominguez H., Ferrante M.
      Innovative method in microalgae processing for environmental and health applications.
      3rd International One Health Conference, October 15–17, 2024, Athens (Greece).


    • Thesis Supervision (Co-Supervisor)

    • Stefania Indelicato – Toxicity evaluation of brookite TiO nanoparticles combined with CeO on marine invertebrate spermatozoa.
      MSc in Health and Cellular-Molecular Biology, University of Catania
    • Miriam Ficicchia – Effects of non-ionizing EMFs at 27 GHz on spermatozoa of Mytilus galloprovincialis.
      MSc in Health and Cellular-Molecular Biology, University of Catania

 

PhD Program in Earth and Environmental Sciences – Cycle XXXVIII

Project Title: In Silico-study for the evaluation of oncoprotective activity by analysis of highly purified algal phycocyanin through miRNAs regulation


Book Chapter Contribution

  1. Co-author of the university textbook “Environmental Hygiene”, 1st edition (2024), ISBN 9788836232031.

Awards

1st Prize – Euro-Mediterranean Journal Paper Award
2nd International One Health Conference 2023

  • Authors: Sica C., Oliveri Conti G., Copat C., Bonfante G., Nicotra P., Scollo M., Falqui L., Ferrante M.

  • Title: The DECARB project as a One Health approach in industrial symbiosis


Conferences and Scientific Presentations

1. Sica C., Scalisi E.M., Ignoto S., Palmeri L., Contino M., Ferruggia G., Salvaggio A., Pavone S.C., Sorbello G., Di Donato L., Pecoraro R., Brundo M.V.
Effect of electromagnetic fields at 27 GHz on sperm quality of Mytilus galloprovincialis.
ICEB 2021 – 15th International Conference on Environment and Bioengineering, December 13–14, 2021, Cairo (Egypt).

2. Ignoto S., Scalisi E.M., Sica C., Contino M., Ferruggia G., Salvaggio A., Pavone S.C., Sorbello G., Di Donato L., Pecoraro R., Brundo M.V.
Non-invasive technique for measuring heartbeat in zebrafish embryos exposed to electromagnetic fields at 27 GHz.
ICEB 2021 – 15th International Conference on Environment and Bioengineering, December 13–14, 2021, Cairo (Egypt).

3. Sica C., Pecoraro R., Pavone C.S., Sorbello G., Di Donato L., Ignoto S., Scalisi E.M., Ferruggia G., Contino M., Salvaggio A., Brundo M.V.
Biological effects of non-ionizing electromagnetic fields on reproduction of Mytilus galloprovincialis.
XXVI National SIPI Congress, June 23–25, 2022, Messina (Italy).

4. Ferruggia G., Pecoraro R., Contino M., Ignoto S., Sica C., Truglio E., Ilaria C., Brundo M.V., Salvaggio A.
Traditional and innovative techniques for evaluating the embryotoxicity of TiO₂ nanoparticles on zebrafish larvae.
XXVI National SIPI Congress, June 23–25, 2022, Messina (Italy).

5. Indelicato S., Sica C., Contino M., Ferruggia G., Pecoraro R., Scalisi E.M., Brundo M.V., Pennisi S., Coppa F., Giuffrida G.
Toxicity evaluation of Brookite-phase TiO₂ nanoparticles combined with CeO₂ on sperm cells of marine invertebrates.
1st National Conference “Emerging Contaminants: Environment, Nutrition, Health”, ONB, Catania (Italy).

6. Contino M., Ferruggia G., Sica C., Indelicato S., Pecoraro R., Scalisi E.M., Brundo M.V.
Toxicity of polystyrene nanospheres on human sperm cells.
1st National Conference “Emerging Contaminants: Environment, Nutrition, Health”, ONB, Catania (Italy).

7. Sica C., Oliveri Conti G., Copat C., Bonfante G., Ferrante M.
The DECARB Project as a One Health approach in industrial symbiosis.
2nd International One Health Conference, October 19–20, 2023, Barcelona (Spain).

8. Copat C., Grasso A., Falqui L., Scollo M., Favara C., Sica C., Cristaldi A., Fiore M., Oliveri Conti G., Ferrante M.
Conversion of greenhouse gas emissions (CO₂) into algal biomass for the production of bioactive antitumor compounds: Implementing green industrial symbiosis to support preventive medicine (GrEEnoncoprev – REACT-EU).
2nd International One Health Conference, October 19–20, 2023, Barcelona (Spain).

9. Copat C., Scollo M., Bonfante G., Favara C., Sica C., Grasso A., Oliveri Conti G., Ferrante M.
Microalgae solution to fight climate change and support green economy: new challenges with Haematococcus pluvialis cultivation.
International Conference: Climate Change and Environmental Pollutants – Main Drivers of Biodiversity Decline, November 2023, Sousse (Tunisia).

10. Sica C., Inoubli S., Favara C., Copat C., Torres M.D., Bonfante G., Falqui L., Scollo M., Oliveri Conti G., Dominguez H., Ferrante M.
From Photobioreactors to Preventive Medicine: The Role of Microalgae in the Energy Transition.
VII Annual Meeting, July 18–19, 2024, University of Vigo, Campus of Marcosende (Spain).

11. Inoubli S., Sica C., Florez-Fernandez N., Diaz-Reinos B., Torres M.D., Dominguez H.
Supercritical-CO₂ extraction of lipidic, phenolic, and pigment fractions from Rugulopteryx okamurae.
3rd Iberian Meeting on Supercritical Fluids, July 22–24, 2024, Ourense (Spain).

12. Sica C., Favara C., Copat C., Torres M.D., Florez-Fernandez N., Bonfante G., Falqui L., Scollo M., Oliveri Conti G., Dominguez H., Ferrante M.
Arthrospira platensis biorefinery for the production of green cosmetics-based products.
5th Iberoamerican Congress on Biorefineries (5-CIAB), October 2–4, 2024, Jaén (Spain).

13. Sica C., Favara C., Inoubli S., Copat C., Torres M.D., Bonfante G., Falqui L., Scollo M., Oliveri Conti G., Dominguez H., Ferrante M.
Innovative method in microalgae processing for environmental and health applications.
3rd International One Health Conference, October 15–17, 2024, Athens (Greece).


Co-Supervision / Co-Advisor Roles

1. Stefania Indelicato
Thesis Title: Toxicity evaluation of Brookite-phase TiO₂ nanoparticles combined with CeO₂ on sperm cells of marine invertebrates
Master’s Degree in Health and Molecular-Cellular Biology, University of Catania.

2. Miriam Ficicchia
Thesis Title: Effects of non-ionizing electromagnetic fields at 27 GHz on sperm cells of Mytilus galloprovincialis
Master’s Degree in Health and Molecular-Cellular Biology, University of Catania.


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